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1.
J Comp Eff Res ; 10(11): 893-897, 2021 08.
Article in English | MEDLINE | ID: covidwho-2269904

ABSTRACT

Aim: To examine the economic impact of lives lost due to the COVID-19 pandemic across New York State. Materials & methods: Death counts by age range and period life expectancy were extracted from the NYS Department of Health, NYC Department of Health and Mental Hygiene, and Social Security Administration website. Years of potential life lost and value of statistical life (VSL) were calculated. Results: The average years of potential life lost per person was 12.72 and 15.13, and the VSL was US$119.62 and 90.45 billion, in NYS and NYC, respectively. VSL was greatest in Queens and Brooklyn, followed by the Bronx, Manhattan and Staten Island. Conclusion: New York City, specifically Queens and Brooklyn, bore the greatest economic burden of lives lost across the state.


Subject(s)
COVID-19 , Cost of Illness , Humans , New York City/epidemiology , Pandemics , SARS-CoV-2
2.
J Comp Eff Res ; 11(9): 689-698, 2022 06.
Article in English | MEDLINE | ID: covidwho-2254396

ABSTRACT

Aim: To provide a comprehensive understanding of the varying effects of SARS-CoV-2 infection based on sex. Methods: A PubMed search of 470 primary articles was performed, with inclusion based on relevance (sex differences discussed in the target COVID population) and redundancy. PubMed was queried based on title for the keywords "SEX" and "COVID" or "SARS" between 2020 and 2022. Results: For COVID-19, males have increased risk for infectivity and intensive care unit admission and worse overall outcomes compared with females. Genetic predispositions, sex hormones, immune system responses and non-biological causes all contribute to the disparity in COVID-19 responses between the sexes. COVID-19 sex-related determinants of morbidity and mortality remain unclear. Conclusions: Male sex is a risk factor for several overall worse outcomes related to COVID-19. Investigating the sex impact of COVID-19 is an important part of understanding the behavior of the disease. Future work is needed to further explore these relationships and optimize the management of COVID-19 patients based on sex.


Subject(s)
COVID-19 , Female , Hospitalization , Humans , Intensive Care Units , Male , SARS-CoV-2 , Sex Factors
3.
J Comp Eff Res ; 11(9): 643-648, 2022 06.
Article in English | MEDLINE | ID: covidwho-1902853

ABSTRACT

Aim: To evaluate the impact of the COVID-19 pandemic on the economic burden of drug overdose deaths in the USA. Methods: Overdose death counts from 2019 to 2020 were obtained from the CDC's National Vital Statistics System. Years of potential life lost and value of statistical life were computed. Results: The financial burden of overdose deaths increased by nearly 30%, from US$624.90 billion before the pandemic in 2019 to US$825.31 billion during the pandemic in 2020. Temporal analysis demonstrated that overdose deaths peaked in the second quarter of 2020 and contributed to nearly a third of the total 2020 value of statistical life. Conclusion: The authors' findings suggest that the COVID-19 pandemic has exacerbated the US drug overdose epidemic.


Subject(s)
COVID-19 , Drug Overdose , Drug Overdose/epidemiology , Financial Stress , Humans , Pandemics , United States/epidemiology
4.
J Comp Eff Res ; 11(7): 489-498, 2022 05.
Article in English | MEDLINE | ID: covidwho-1736659

ABSTRACT

Aim: To examine the economic impact of lives lost due to the coronavirus pandemic across California and Los Angeles (LA) County. Patients & methods: Years of potential life lost (YPLL) and the value of statistical life (VSL) were calculated using mortality data from the California Department of Public Health, the LA County Department of Public Health and the Social Security Administration websites. Results: In California and LA County, the average YPLL per person were 14.3 and 14.7 and the VSLs were approximately US$219.9 billion and $82.7 billion, respectively. YPLL and VSL were greatest for Latinos aged 50-64. Conclusion: The economic burden of lives lost due to the coronavirus across California and LA County is substantial. Latinos aged 50-64 were most affected.


Subject(s)
COVID-19 , California/epidemiology , Financial Stress , Humans , Pandemics , Public Health
5.
J Comp Eff Res ; 11(5): 371-381, 2022 04.
Article in English | MEDLINE | ID: covidwho-1622526

ABSTRACT

This narrative review summarizes recent reports to provide an updated understanding of the multiorgan effects of SARS-CoV-2 infection in obese individuals. A PubMed search of 528 primary articles was performed, with inclusion based on novelty, relevance and redundancy. Obesity confers an increased risk for hospitalization, intensive care unit admission, severe pneumonia, intubation and acute kidney injury in COVID-19 patients. Obesity is also associated with higher levels of inflammatory and thrombotic markers. However, the associations between obesity and mortality or cardiac injury in COVID-19 patients remain unclear. Obesity is a risk factor for several respiratory and nonrespiratory COVID-19 complications. Future work is needed to further explore these relationships and optimize the management of obese COVID-19 patients.


Subject(s)
COVID-19 , Hospitalization , Humans , Intensive Care Units , Obesity/complications , Risk Factors , SARS-CoV-2
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